gap junction protein การใช้

• Closure of gap junction protein channels is a normal precursor to cell division.
• This gene encodes a gap junction protein.
• Gap junctions are critical for cardiac myocytes, mice and humans deficient in a particular gap junction protein have severe heart development defects.
• Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains.
• It was suggested that vinnexins may function to alter gap junction proteins in infected host cells, possibly modifying cell-cell communication during encapsulation responses in parasitized insects.
• Its role in controlling cell motility and polarity was thought to contribute to cancer development and metastasis, though its role as a gap junction protein may also be involved.
• "' Connexins ( Cx ) "'( TC # 1 . A . 24 ), or gap junction proteins, are structurally related transmembrane proteins that assemble to form vertebrate gap junctions.
• Numerous perturbations affecting the cardiac neural crest have been associated with persistent truncus arteriosus, some of which include growth factors ( fibroblast growth factor 8 and bone morphogenetic protein ), transcription factors ( T-box, Pax, Nkx2-5, GATA-6, and Forkhead ), and gap junction proteins ( Connexin ).